Abstract
Introduction: The purpose of this study was to evaluate the antimicrobial effects of zinc oxide nanoparticles on human bacteria.
Methods: The commercially available zinc oxide nanoparticles were purchased. The studied bacteria were purchased as
lipophilic ampoules from Iranian Fungal and Bacterial Collection. Finally, the minimum inhibitory concentration and minimum
bactericidal concentration were determined by the microdilution method.
Results: The results of this study showed that the maximum inhibitory concentration of zinc oxide nanoparticles was 1500 μg/
mL against Staphylococcus aureus and Streptococcus pyogenes. While the minimum inhibitory concentration was 187 μg/mL
against Acinetobacter baumannii. The maximum bactericidal concentration (3000 μg/mL) was observed against S. aureus. While
the minimum bactericidal concentration was observed against Acinetobacter baumannii.
Conclusion: Based on our results, zinc oxide nanoparticles have a good antimicrobial activity against bacteria.