Journal of Nano Drug Science
Submitted: 07 Jul 2019
Accepted: 10 Oct 2018
First published online: 17 Dec 2018
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Journal of Nano Drug Science. 2018;1(1):5-9.
  Abstract View: 909
  PDF Download: 627

Original Article

Synthesis of Silver Nanoparticles Using Verbena officinalis Plant Extract and Investigation of the Antimicrobial Activity Against Acinetobacter baumannii Bacteria

Ali Sanchooli 1, Zahra Yazdanpour 2 *

1 abol Medicinal Plant Research Center, Zabol University of Medical Sciences, Zabol, Iran
2 Department of Microbiology, Faculty of Medicine, Zabol University of Medical Sciences, Zabol, Iran
*Corresponding author: Zahra Yazdanpour, Email: Email:


Introduction: The aim of this study was to synthesize silver nanoparticles (AgNPs) using Verbena officinalis plant extract and to investigate the antimicrobial activity against Acinetobacter baumannii bacteria isolated from patients in Zabol.

Methods: AgNPs were obtained through reacting silver nitrate solution 2 mM and V. officinalis leaf extract. The AgNPs were characterized by ultraviolet–visible (UV-Vis) spectrophotometer, scanning electron microscopy (SEM), and Fourier-transform infrared spectroscopy (FTIR). To determine minimum inhibitory concentration and to test antibiogram of nanoparticle synthesized, broth micro dilution methods were used, respectively.

Results: Nanoparticles were formed with an average size of 42.57 ± 5.34 nm. The results of this study showed that synthetic nanoparticles in the V. officinalis plant extract were good inhibitors of antibiotics resistant A. baumannii so that the lowest inhibitory concentration was 3.1 μL/mL.

Conclusion: The results clearly indicated that V. officinalis AgNPs had a potential antimicrobial activity against A. baumannii.

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