Journal of Nano Drug Science
Submitted: 01 Jan 2018
Accepted: 01 Jan 2018
First published online: 01 Jan 2018
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Journal of Nano Drug Science. 2018;1(1):22-24.
  Abstract View: 100
  PDF Download: 86

Brief Report

Evaluation of Antimicrobial Activity of Zinc Oxide  Nanoparticles Against Human Pathogens

Masoume Farsizaban 1, Mahsa Poorjangi 2 * , Mohammad Javad Keikhaie Farzane 3

1 Department of Medical Physics, Zahedan University of Medical Sciences, Zahedan, Iran
2 Student Research Committee, Zahedan University of Medical Sciences, zahedan, Iran
3 Zahedan Health Promotion Research Center, Zahedan University of Medical Sciences, Zahedan, Iran
*Corresponding Author: Mahsa Poorjangi, Email: Email: MahsaPoorjangi@yahoo.com

Abstract

Introduction: The purpose of this study was to evaluate the antimicrobial effects of zinc oxide nanoparticles on human bacteria.

Methods: The commercially available zinc oxide nanoparticles were purchased. The studied bacteria were purchased as lipophilic ampoules from Iranian Fungal and Bacterial Collection. Finally, the minimum inhibitory concentration and minimum bactericidal concentration were determined by the microdilution method.

Results: The results of this study showed that the maximum inhibitory concentration of zinc oxide nanoparticles was 1500 μg/ mL against Staphylococcus aureus and Streptococcus pyogenes. While the minimum inhibitory concentration was 187 μg/mL against Acinetobacter baumannii. The maximum bactericidal concentration (3000 μg/mL) was observed against S. aureus. While the minimum bactericidal concentration was observed against Acinetobacter baumannii.

Conclusion: Based on our results, zinc oxide nanoparticles have a good antimicrobial activity against bacteria.

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